How https://www.ceesdekker.net can Save You Time, Stress, and Money.
How https://www.ceesdekker.net can Save You Time, Stress, and Money.
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Rotary motion of DNA rotors on nanopores. Top rated row: raw online video on the Cy5 channel of each rotor. Center row: corresponding single-particle localization benefits of each finishes with the DNA rotors. The place of the present frame is marked as orange and blue dots, as well as trajectory of the 10 frames right before The present body is proven as solid traces.
Human Rad51 filaments on double- and solitary-stranded DNA: correlating frequent and irregular types with recombination purpose.
Multicolor imaging of your bacterial nucleoid and mobile division proteins with blue, orange, and around-infrared fluorescent proteins
2007, very first serious-time detection of strand Trade in homologous recombination by RecA; discovery of the reduced persistence size of ends of microtubules; and fixed the system of biosensing with carbon nanotubes
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Experimental section diagram of negatively supercoiled DNA measured by magnetic tweezers and fluorescence,
MATLAB codes for info processing can be found at . Julia codes useful for numerical simulation can be obtained at .
2000, discovery that nanotubes can carry incredible big latest densities; resolved the controversial situation of Digital transportation via DNA molecules by measurements of insulating habits at The one molecule level; and demonstration of an AFM procedure for one-molecule manipulation of nanotubes
Understanding essential procedures regulating the spatial and dynamic organisation of your DNA in Are living cells.
Dekker started off his analysis on single carbon nanotubes in 1993 when he build a whole new line of study to check electrical transport through solitary natural molecules concerning nanoelectrodes. In 1996 a breakthrough was recognized with carbon nanotubes. This was achieved in a very collaboration With all the team of Nobel laureate ceesdekker Richard Smalley. STM and nanolithography strategies were accustomed to demonstrate that these nanotubes are quantum wires at The only-molecule level, with fantastic physical Homes.
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Cees Dekker is Distinguished University Professor at TU Delft. Trained as a physicist, he pioneered nanotechnology with many discoveries on carbon nanotubes in the nineteen nineties. Considering the fact that 2000, he moved to one-molecule biophysics and nanobiology. His latest exploration concentrates on (i) nanopores for protein sequencing; (ii) chromosome framework, particularly SMC motor protein; and (iii) building a living synthetic mobile from lifeless molecules. Dekker is really an elected member on the KNAW and fellow for the APS as well as the IOP.
Developments in nanotechnology in the nineteen nineties made building electronic devices from one molecules a risk. Cees Dekker recounts how his workforce created a room-temperature transistor based on a single carbon nanotube.
Supercoiling-dependent DNA binding: quantitative modeling and programs to bulk and one-molecule experiments